Jiaojiao Li

2021-11-22 By:



College of Ecology and Environmental Sciences, Yunnan University, Kunming, 650091, PR China.

Office: Building ShiXun 1501-7,YNU

Phone: 18088260774

Email: jiaojiaoli@ynu.edu.cn

WeChat: lp20100104

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2012-2017 PhD: Department of Cellular Biology and Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, United States. Major: Biomedical Sciences

2005-2010 MD: College of Clinical Medicine, Kunming Medical University, Kunming, Yunnan, China. Major: Clinical Medicine

Areas of interest/specialization

1. Environmental toxicology: this research contributions include identification and/or characterization of Secondary metabolites of cyanobacteria blooms, development ecotoxicology of Harmful Algal Blooms (HABs); process xenobiotics or endobiotics metabolism and detoxification pathway in human, animal, microbiome and plant.

2. Adverse outcome pathway: this research aims to identify and sequence the molecular and cellular events to evaluate the toxicity of specific environmental pollutants. Describe the progression of a toxicity pathway from molecular perturbation to cell to tissue to organ to organism to population-level outcome in a series of measurable, mechanistic responses.

Selected publications

1. Jiaojiao Li, Chunxiao Sun, Wenwen Cai, Barry P. Rosen, Jian Chen. Insights into S-adenosyl-L-methionine (SAM)-dependent methyltransferase related diseases and genetic polymorphisms. Mutation Research/Reviews in Mutation Research. 2021, 108396, ISSN 1383-5742, https://doi.org/10.1016/j.mrrev.2021.108396.

2. Li, J. J, L. Yang, C . P. Miao, Y. J. Teng, Z. H. Fu, C. L. Cheng, X. X. Chang, Y. Qian, and L. X. Zhao. 2021. Impact of rhizosphere microorganisms on arsenic (As) transformation and accumulation in a traditional Chinese medical plant. Environ Sci Pollut Res Int. 2021 Nov;28(43):60923-60934. doi: 10.1007/s11356-021-14500-6. Epub 2021 Jun 24. PMID: 34165739.

3. Jiaojiao LiCharles PackianathanToby G. RossmanBarry P. Rosen, Nonsynonymous Polymorphisms in the Human As3mt Arsenic Methylation Gene: Implications for Arsenic Toxicity, Chemical Research in Toxicology, 2017, 30 (7): 1481-1491.

4. Jiaojiao LiShashank S. PawitwarBarry P. Rosen, The Organoarsenical Biocycle and the Primordial Antibiotic Methylarsenite, Metallomics, 2016, 8 (10): 1047-1055.

5. Jiaojiao LiGoutam MandalBarry P. Rosen, Expression of Arsenic Resistance Genes in the Obligate Anaerobe Bacteroides Vulgatus Atcc 8482, a Gut Microbiome Bacterium, Anaerobe, 2016, 39: 117-123

Active grants

Project: Adverse outcome pathways of extracellular exudates of Cyanobacteria and its main component phytosphingosine

Role: Principal Investigator
Sponsor: National Natural Science Foundation of China
Period: Jan 2022– Dec 2024
Total Funding: ¥240,000
Status: Active

Project: Teratogenicity of tretinoids from cyanobacteria extracellular exudates.

Role: Principal Investigator
Sponsor: Science and Technology Department of Yunnan Province
Period: Jan 2021– Dec 2023
Total Funding: ¥50,000
Status: Active